Tuberose Sclerosis with Intracranial Calcification and Lesions of Bone

Two Cases of Tuberose Sclerosis

Tuberous sclerosis: evaluation of intracranial lesions

The objective of this pictorial essay is to describe and provide examples of intracranial imaging findings of tuberous sclerosis (TS) extracted from our case series. Tuberous sclerosis is a neurocutaneous syndrome formerly described by Bourneville in 18801 (also known as Bourneville disease). This entity is an inherited autosomal dominant disease caused by mutation or deletion of two genes: one...

Prevalence and calcification of intracranial arterial stenotic lesions as assessed with multidetector computed tomography angiography.

BACKGROUND AND PURPOSE Intracranial arterial stenosis (ICAS) in patients with recent ischemic stroke is associated with a high risk of recurrent stroke. More insight into the pathophysiology of ICAS could help identify patients at high risk requiring more aggressive secondary prevention. We evaluated the prevalence, distribution, calcification, and the risk factors predisposing ICAS in a Europe...

Pathognomonic intracranial calcification.

Non-pathological intracranial calcification is common in the pineal, choroid plexus and in the falx cerebri and is readily recognizable by their positions. Large calcifications can occur in a pinealoma, in the choroid plexus in tuberous sclerosis and neurofibromatosis and at the falx with a meningioma. Healed granulomas, especially tuberculosis and parasites, can produce small single or scatter...

Hereditary folate malabsorption with extensive intracranial calcification.

BACKGROUND Anemia is a common accompaniment of cerebral palsy, mental retardation and neurodegenerative disorders. CLINICAL CHARACTERISTICS A 4-year-old boy with chronic megaloblastic anemia, global developmental delay, seizures, intracranial calcification and new onset neuro-regression. OBSERVATION A diagnosis of hereditary folate malabsorption was made, and he was put on oral and injectab...